Dry eye syndrome

27 July 2017 in In Vivo

Dry eye syndrome (keratoconjunctivitis sicca, KCS) is a multifactorial disease of the tear glands and ocular surface. We offer a mouse model of KCS, which is induced by exposure to a novel desiccating environment chamber (SiccaSystemTM, K&P Scientific LLC, IL).

Our references:

Žiniauskaitė A, Ragauskas S, Puranen J, Haapaniemi AM, Kalesnykas G, Kaja S. Restasis® prevents lacrimal gland pathology in the novel SiccaSystemTM standardized experimental platform for experimental dry-eye disease research. ARVO 2016, abstract no.: 5690.

Kaja S, Koulen P, Puranen J, Ragauskas S. A topically delivered synthetic metalloporphyrin SOD mimetic improves hallmarks of dry-eye disease pathology. ARVO 2016, abstract no.: 396.

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