Author: tandemum

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A retinal organotypic model for ex vivo neuroprotection studies

A retinal organotypic model for ex vivo neuroprotection studies

A recently published study by Experimentica Ltd. and its collaborators from the University of Tampere, Finland, shows that when the functional and morphological read-outs of retinal explant cultures are combined, it creates a valuable tool for studying retinal viability & degeneration, establishing a novel platform on which to test new therapeutic applications, aimed at treating […]
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Advances in preclinical in vivo imaging: OCT-Angiography of the rat retina

Advances in preclinical in vivo imaging: OCT-Angiography of the rat retina

Optical Coherence Tomography Angiography (OCT-A) is a novel non-invasive imaging technique to generate high resolution images of the retinal and choroidal microvasculature. By using motion contrast imaging, OCT-A can generate angiographic images without the need for intravenous dye injection.
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Experimentica Ltd. adds optic neuritis model to the Preclinical Model portfolio

Experimentica Ltd. adds optic neuritis model to the Preclinical Model portfolio

Species: mouseFollow-up period: up to 35 daysRoute of compound administration: topical, intravitreal, systemic. Functional and histological read-outs: In vivo imaging (optical coherence tomography (OCT)); In vivo functional assessment: a) electroretinography (pERG), b) visual evoked potentials (VEP); Morphological assessment (histology, IHC, EM, stereology); Molecular biology (ELISA, Western blotting, qPCR). Reference compounds (for MS-associated and ON phenotypes).
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Experimentica Ltd. appoints new director of laboratory animal research

Experimentica Ltd. appoints new director of laboratory animal research

Kuopio, Finland, 25th January 2017: Experimentica Ltd., a global ophthalmic contract research organization (CRO) today announced the appointment of Satu Mering, Ph.D. to Director Laboratory Animal Research. Dr. Mering received both her Masters and Ph.D. degree in Applied zoology from the University of Eastern Finland, where she served as Director of the Laboratory Animal Center […]
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Experimentica Ltd. awarded EU Eurostars funding

Experimentica Ltd. awarded EU Eurostars funding

Kuopio, Finland and Vilnius, Lithuania, September 28th, 2015. Experimentica Ltd. (Finland), Ferentis UAB and State Research Institute Center for Physical Sciences and Technology (Department of Nanoengineering), Lithuania, were awarded a 534 364.00 € funding from the Eurostars programme to develop synthetic human-like corneal models as tools to aid eye drug assessment and screening, and reduce animal testing. […]
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Experimentica Ltd. participates in ORBITAL, an EU Horizon 2020 Marie Sklodowska-Curie Innovative Training Network award

Experimentica Ltd. participates in ORBITAL, an EU Horizon 2020 Marie Sklodowska-Curie Innovative Training Network award

Experimentica Ltd. is pleased to announce its participation as beneficiary in the ORBITAL consortium who were awarded a Horizon 2020 framework Marie Sklodowska-Curie Innovative Training Network award. The ORBITAL (Ocular Research By Integrated Training And Learning) consortium, led by Dr. Laurence Fitzhenry at The Waterford Institute, Ireland, received €4M from the European Training Network (ETN) programme to […]
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Experimentica Ltd. Presents at the ISER in Belfast, Northern Ireland

Experimentica Ltd. Presents at the ISER in Belfast, Northern Ireland

The XXXIII Biennial Meeting of the International Society of Eye Research takes place this year from September 9-13th in Belfast, Northern Ireland, UK.  Dr Jenni J. Hakkarainen – Acting Chief Operating Officer of Experimentica Ltd. will present an oral presentation entitled: Protection by a metalloporphyrin superoxide dismutase mimetic against signs of dry-eye disease Dr Simon Kaja – […]
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Experimentica Ltd. presents strategic roadmap and announces €3,05M investment in artificial intelligence for preclinical efficacy and safety testing of ophthalmic drug candidates

Experimentica Ltd. presents strategic roadmap and announces €3,05M investment in artificial intelligence for preclinical efficacy and safety testing of ophthalmic drug candidates

Experimentica Ltd. revealed its strategic plan that outlines a roadmap for the development of artificial intelligence (AI)-based algorithms aimed at quantifying and predicting the preclinical efficacy and safety of next-generation drugs for ophthalmic indications.
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Experimentica Ltd. Sponsors the 2018 SILK-Elsemay Björn Symposium

Experimentica Ltd. Sponsors the 2018 SILK-Elsemay Björn Symposium

[Kuopio, Finland and Chicago, USA – August 14th, 2018] – Experimentica Ltd. is pleased to announce its co-sponsorship and participation in this year’s SILK – Elsemay Björn Symposium. This yearly international symposium is to be held in Tampere, Finland at the Jarmo Visakorpi Auditorium, Arvo Ylpön katu 34, Tampere on August 20th, 2018. Experimentica Ltd. is a co-sponsor with SILK […]
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In vivo imaging in the rat oxygen-induced retinopathy model

In vivo imaging in the rat oxygen-induced retinopathy model

Background Oxygen-induced retinopathy model mimics retinopathy of prematurity and human ischemic retinopathies. Retinopathy of prematurity (ROP) affects premature infants that weigh less than 1,250 grams or that are born before 31 weeks of gestation. ROP is a potentially blinding eye disorder. As advances in care for premature neonates have reduced the impact of ROP, a […]
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Jeff Jamison receives Department Merit Award from Michigan Engineering

Jeff Jamison receives Department Merit Award from Michigan Engineering

Our colleague Jeff Jamison last week received the Biomedical Engineering Department Merit Award from University of Michigan College of Engineering. Michigan Engineering honors those alumni who personify the College’s tradition of excellence. Department Merit Awards recognize distinction at the academic department level. Congratulations from all of us at Experimentica, Jeff!
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Meet Experimentica Ltd. in Vienna at the EURETINA 2018, Congress

Meet Experimentica Ltd. in Vienna at the EURETINA 2018, Congress

Experimentica representatives and scientists will be attending the 18th EURETINA Congress in Vienna, Austria. The event takes place from the 20th– 23rd of September at the Messe Wien Exhibition & Congress Centre: Entrance D, Trabrennstraße 7, 1021 Vienna, Austria U2. (Subway station: Krieau) To contact an Experimentica representative please e-mail info@experimentica.com [Kuopio, Finland and Chicago, USA – September 18th, 2018]– Experimentica […]
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The End of BAC containing ophthalmic formulations?

The End of BAC containing ophthalmic formulations?

Acute cytotoxic effects of the pharmaceutical excipients benzalkonium chloride (BAC), macrogolglycerol hydroxystearate (MGHS40), polysorbate 80 (PS80) and marketed ophthalmic formulations (Lumigan(R), Monoprost(R), Taflotan(R), Travatan(R), Xalatan(R)) containing these excipients were tested. Human corneal epithelial cell (HCE-T) viability was assessed by measuring the reduction of resazurin to highly fluorescent resorufin. The study was fully funded by Experimentica […]
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Visit our poster in 17th European Congress of Toxicologic Pathology

Visit our poster in 17th European Congress of Toxicologic Pathology

A chance for ESTP 2019 participants! Experimentica’s partner Aiforia Technologies Oy will present joint poster dedicated for illustration of the effectivity of Aflibercept, administered systemically and for initial demonstration of convolutional neural network trained to recognize and quantify choroidal neovascularization lesion using Aiforia® Cloud. The poster will be presented during 17-19th of September, 2019 in 17th European Congress of Toxicologic Pathology, Cologne, […]
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