Experimentica’s Research & Development Division is actively implementing in vitro models previously described in the scientific literature for a number of customer oriented approaches. Some of our current activities include the development of artificial corneas for permeability screening.

Utilizing cell biology (using primary cells and cell lines), molecular biology, immunocytochemical imaging and multi-mode microplate reader applications, we are able to measure several molecular mechanisms, protein expressions and cellular functions.

We look forward to an opportunity to partner with you to refine or develop almost any custom in vitro project.

• Hakkarainen JJ, Reinisalo M, Ragauskas S, Seppänen A, Kaja S, Kalesnykas G. Acute cytotoxic effects of marketed ophthalmic formulations on human corneal epithelial cells. Int J Pharm. 2016;511(1):73-78. doi: 10.1016/j.ijpharm.2016.06.135.

• Hakkarainen JJ, Maruotti J, Seppänen, Onteniente B, Kalesnykas G, Reinisalo M. hiPSC-derived RPE cells: Characterization of blood-retinal barrier properties and drug permeability. ARVO2016 Poster. Invest. Ophthalmol. Vis. Sci. 2016, Vol.57, 268.