Summary: This study aimed at determining the properties of primary ONHA-derived exosomes, their uptake into primary neurons, and to identify the functional effects of exosomes on neuronal survival and neurite outgrowth.
Abstract
ARVO advances research worldwide into understanding the visual system and preventing, treating and curing its disorders. This year again the work of Experimentica’s scientists at the forefront of Ophthalmology research was featured at the 2021 ARVO Annual Meeting.
Extracellular vesicles (exosomes) derived from primary optic nerve head astrocytes enhance neurite outgrowth
The aim of this study was to determine the properties of primary optic nerve head astrocyte (ONHA)-derived extracellular vesicles (exosomes), their uptake into primary neurons, and to identify the functional effects of exosomes on neuronal survival and neurite outgrowth.
Authors: Simon Kaja | Harsh Hariani | Anita Ghosh | Giedrius Kalesnykas | Walter K. Jones