Life Sciences Baltics 2025
Come to meet us on our home turf in Vilnius! We are pleased to invite you to visit our booth at Life Sciences Baltics 2025 taking place on September 17–18 in Vilnius, Lithuania.
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Faster results for in vitro corneal permeability studies
At Experimentica, we are committed to advancing R&D and continuously improving established study methods. Our work is guided by three core principles: quality, flexibility, and scientific excellence, all of which support our commitment to be a trusted partner for our clients. In collaboration with Finnadvance Ltd, we validated the AKITA® platform combined with human corneal epithelial cells which has yielded substantial advancements in in vitro corneal permeability studies.
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Experimentica Appoints Dr. Artem Shatillo as Director, Digital Transformation
Experimentica Ltd., a trusted partner in preclinical drug development for ocular diseases, is excited to announce the appointment of Dr. Artem Shatillo as Director of Digital Transformation, effective July 1, 2025.
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FELASA 2025 presentation: Assessing lidocaine-based analgesia for mouse ear notching: Insights into strain-specific reactions
From the beginning of 2024, a new national law on animal protection in Finland (1165/2023 3 §) requires laboratory rodent ear notching to be performed only with "appropriate pain relief". However, the European Union directive on the protection of animals used for scientific purposes (2010/63/EU) classifies ear notching as a routine identification method rather than a procedure, leaving no specific guidelines on suitable analgesia at the EU or the national level. This study aimed to evaluate the suitability of a lidocaine-based cream as analgesia (EMLA cream 5%, lidocaine + prilocaine 25+25 mg/g, Aspen Pharmacare Australia) for mice undergoing ear notching.
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Experimentica presents at FELASA 2025
At Experimentica, animal welfare is a core principle of our work. We are dedicated to include refinement studies as part of our internal R&D to improve the well-being of animals involved.
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ARVO 2025 presentation: Morphological, functional, and behavioral alterations in a microbead-induced mouse glaucoma model
The main aim of the study was to examine the correlation of ocular hypertension with morphological, functional and behavioural parameters in the mouse magnetic microbead glaucoma model.
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ARVO 2025 presentation: Combined administration of BDNF and CNTF provides superior neuroprotection as compared to BDNF alone in a mouse optic nerve crush model
Glaucoma, a leading cause of blindness and visual impairment worldwide, is characterized by progressive loss of retinal ganglion cells (RGCs) and damage to the optic nerve. Neurotrophic factors, including brain-derived neurotrophic factor (BDNF) and ciliary neurotrophic factor (CNTF), have been extensively studied for their potential to promote RGC survival and axonal regeneration. However, BDNF's efficacy is restricted by receptor desensitization, while CNTF alone often induces inflammation and gliosis, limiting its therapeutic potential. This study was aimed at evaluating if a combination of BDNF and CNTF offers synergistic effects, providing superior neuroprotection as compared to either factor alone.
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ARVO 2025 presentation: Human cornea-on-a-chip – opportunities and challenges
Cornea is a tight barrier restricting topically administered drugs’ penetration into the eye. The aim of the study was to create a tight epithelial barrier both with primary and with transformed human corneal cells on a 96-well microfluidic platform.
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ARVO 2025 presentation: Comparison of blue light-induced damage (BLD) in albino and pigmented mice
This study aimed at comparing blue light-induced retinal injury in albino Balb/cJRj and pigmented C57BL/6JRj mice.
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ARVO 2025 presentation: Triamcinolone delays retinal atrophy in a mouse laser-induced geographic atrophy model
Limited treatment options for patients with geographic atrophy (GA) pose challenges to find proper positive controls in preclinical models. This study aimed to test the efficacy of subconjunctival administration of triamcinolone in a laser-induced mouse model of GA.
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