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A mouse model for Dry Eye Disease

A mouse model for Dry Eye Disease

Experimentica utilizes a validated mouse model of dry eye disease. Dry eye disease-like pathology is induced using transdermal scopolamine patches in combination with desiccating environmental stress. The induced pathology is characterized using corneal fluorescein staining, tear volume measurements, and histology for lacrimal gland infiltration, goblet cell loss, and corneal abnormalities.

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Modeling Diabetic Retinopathy in rodents

Modeling Diabetic Retinopathy in rodents

A brief overview of streptozotocin-induced diabetic retinopathy in rodents, highlighting strain-specific differences, quantitative assessment of retinal vascular leakage, identification of the most consistent and reliable readout, and animal welfare considerations.

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Comprehensive characterization of the rat magnetic microbead model

Comprehensive characterization of the rat magnetic microbead model

Glaucoma is a leading cause of irreversible blindness, highlighting the urgent need for reliable preclinical models that capture both structural and functional disease aspects. Our recently published study by Kernius Mickevičius provides a longitudinal evaluation of the rat magnetic microbead model of ocular hypertension by combining multimodal monitoring tools including spectral-domain optical coherence tomography (SD-OCT), pattern electroretinography (pERG), optomotor testing, and morphological analysis.

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AAALAC accredited company

All our facilities are AAALAC accredited, reflecting our commitment to the highest standards of animal care in research.