Skip to content
ARVO 2025 presentation: Phosphate-buffered saline administered intravitreally at P12 blocks neovascularization in the mouse oxygen-induced retinopathy model

ARVO 2025 presentation: Phosphate-buffered saline administered intravitreally at P12 blocks neovascularization in the mouse oxygen-induced retinopathy model

Intravitreally injected phosphate-buffered saline (PBS) is known to decrease neovascularization in the mouse oxygen-induced retinopathy (OIR) model, and it is commonly used as a vehicle control in preclinical studies evaluating therapeutic efficacy. This study aimed at evaluating the impact of intravitreally (IVT) administered PBS on neovascularization and revascularization at various timepoints after OIR induction. Aflibercept (Eylea®) was used as a reference control.

Learn more Arrow right
AAALAC accredited company

All our facilities are AAALAC accredited, reflecting our commitment to the highest standards of animal care in research.