Summary: This study investigated if chronic moderate alcohol consumption leads to signs of DED in vivo, and to investigate oxidative stress pathways involved in alcohol-induced damage to human corneal epithelial cells in vitro.
Abstract
ARVO advances research worldwide into understanding the visual system and preventing, treating and curing its disorders. This year again the work of Experimentica’s scientists at the forefront of Ophthalmology research was featured at the 2021 ARVO Annual Meeting.
Effects of chronic alcohol administration on the cornea in preclinical models
There is a clinical association between acute and chronic alcohol consumption and the incidence of ocular surface disease, including dry eye disease. The goal of this study was to investigate if chronic moderate alcohol consumption leads to signs of DED in vivo, and to investigate oxidative stress pathways involved in alcohol-induced damage to human corneal epithelial cells in vitro.
Authors: Anita Ghosh | Robertas Cesna | Agne Ziniauskaite | Donatas Neverauskas | Jonathan Eby | Symantas Ragauskas | Simon Kaja