This study defines ocular adenosine metabolism as a complex and spatially integrated network and further characterizes the critical role of CD73 in maintaining the functional activity of retinal cells.

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Optimization of nanoparticule-based antioxidant formulations with the goal to minimize instillation frequency may represent future therapeutic options for dry eye disease and related ocular surface disease.

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The hydrogel-based human corneal model predicts the rabbit corneal permeability more reliably in comparison to HCE-T cells grown in inserts. This in vitro human corneal model can be successfully employed for drug permeability tests whilst avoiding ethical issues and reducing costs.

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Cationic and amphipathic CPPs, transactivator of transcription (TAT), and penetratin can be inferred to be the best among all the identified penetration enhancers for drug delivery to the fundus oculi via topical eye drop instillation.

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Merveilles de couleur dans la rétine - Experimentica designed an AI-based model capable of recognizing and quantifying retinal thickness layers from multiple SD-OCT scans.

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These positive tolerability data underline feasibility of EGF-based interventions in non-rodent models for ocular diseases.

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In an article published in JoVE our R&D Team describes detailed protocols for the OIR model induction and its readouts in both mice and rats.

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