Glaucoma is a leading cause of irreversible blindness, highlighting the urgent need for reliable preclinical models that capture both structural and functional disease aspects. Our recently published study by Kernius Mickevičius provides a longitudinal evaluation of the rat magnetic microbead model of ocular hypertension by combining multimodal monitoring tools including spectral-domain optical coherence tomography (SD-OCT), pattern electroretinography (pERG), optomotor testing, and morphological analysis.
Our latest publication by Anni Tenhunen and colleagues on the welfare outcomes of two widely used rat lines, Brown Norway (BN/Crl) and Sprague Dawley (RjHan:SD), in the STZ-induced diabetic retinopathy model. BN/Crl rats are often favored for ocular studies due to their pigmented eyes, however, our study raises important concerns about their routine use in diabetic models, given their increased risk of serious welfare issues.
Come to meet us on our home turf in Vilnius! We are pleased to invite you to visit our booth at Life Sciences Baltics 2025 taking place on September 17–18 in Vilnius, Lithuania.
At Experimentica, we are committed to advancing R&D and continuously improving established study methods. Our work is guided by three core principles: quality, flexibility, and scientific excellence, all of which support our commitment to be a trusted partner for our clients.
In collaboration with Finnadvance Ltd, we validated the AKITA® platform combined with human corneal epithelial cells which has yielded substantial advancements in in vitro corneal permeability studies.
Experimentica Ltd., a trusted partner in preclinical drug development for ocular diseases, is excited to announce the appointment of Dr. Artem Shatillo as Director of Digital Transformation, effective July 1, 2025.
From the beginning of 2024, a new national law on animal protection in Finland (1165/2023 3 §) requires laboratory rodent ear notching to be performed only with "appropriate pain relief". However, the European Union directive on the protection of animals used for scientific purposes (2010/63/EU) classifies ear notching as a routine identification method rather than a procedure, leaving no specific guidelines on suitable analgesia at the EU or the national level. This study aimed to evaluate the suitability of a lidocaine-based cream as analgesia (EMLA cream 5%, lidocaine + prilocaine 25+25 mg/g, Aspen Pharmacare Australia) for mice undergoing ear notching.
At Experimentica, animal welfare is a core principle of our work. We are dedicated to include refinement studies as part of our internal R&D to improve the well-being of animals involved.
The ARVO 2025 Annual Meeting is just around the corner! Our teams from Finland, Lithuania, and France are getting ready for the trip to Salt Lake City.
All our facilities are AAALAC accredited, reflecting our commitment to the highest standards of animal care in research.
Copyright: Experimentica Ltd. 2025
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