Experimentica utilizes a validated mouse model of dry eye disease. Dry eye disease-like pathology is induced using transdermal scopolamine patches in combination with desiccating environmental stress. The induced pathology is characterized using corneal fluorescein staining, tear volume measurements, and histology for lacrimal gland infiltration, goblet cell loss, and corneal abnormalities.
Join us at Life - the biomedical convention 2026 in Heidelberg! Meet our experts and learn about our ophthalmic preclinical models and ocular tissue analysis.
Experimentica Ltd., a global contract research organization (CRO) dedicated to preclinical models of ophthalmic diseases, announces a significant expansion of its Kuopio site in Finland.
A brief overview of streptozotocin-induced diabetic retinopathy in rodents, highlighting strain-specific differences, quantitative assessment of retinal vascular leakage, identification of the most consistent and reliable readout, and animal welfare considerations.
Glaucoma is a leading cause of irreversible blindness, highlighting the urgent need for reliable preclinical models that capture both structural and functional disease aspects. Our recently published study by Kernius Mickevičius provides a longitudinal evaluation of the rat magnetic microbead model of ocular hypertension by combining multimodal monitoring tools including spectral-domain optical coherence tomography (SD-OCT), pattern electroretinography (pERG), optomotor testing, and morphological analysis.
Our latest publication by Anni Tenhunen and colleagues on the welfare outcomes of two widely used rat lines, Brown Norway (BN/Crl) and Sprague Dawley (RjHan:SD), in the STZ-induced diabetic retinopathy model. BN/Crl rats are often favored for ocular studies due to their pigmented eyes, however, our study raises important concerns about their routine use in diabetic models, given their increased risk of serious welfare issues.
Come to meet us on our home turf in Vilnius! We are pleased to invite you to visit our booth at Life Sciences Baltics 2025 taking place on September 17–18 in Vilnius, Lithuania.
At Experimentica, we are committed to advancing R&D and continuously improving established study methods. Our work is guided by three core principles: quality, flexibility, and scientific excellence, all of which support our commitment to be a trusted partner for our clients.
In collaboration with Finnadvance Ltd, we validated the AKITA® platform combined with human corneal epithelial cells which has yielded substantial advancements in in vitro corneal permeability studies.
All our facilities are AAALAC accredited, reflecting our commitment to the highest standards of animal care in research.
Copyright: Experimentica Ltd. 2026
Manage Consent
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.