Glaucoma, Ocular Hypertension (intraocular pressure, IOP) Glaucoma, Ocular Hypertension (intraocular pressure, IOP) Induced elevation of IOP is widely used as an experimental approach to mimic glaucoma pathology in animals. Related In Vivo Glaucoma Neuroprotection
Optic Nerve Crush (ONC) Optic Nerve Crush (ONC) Crushing the optic nerve with mechanical damage leads to axon degeneration, in turn inducing the apoptotic process in RGCs and, eventually, RGC loss, mimicking glaucomatous neuropathies. Related In Vivo Glaucoma Neuroprotection
Primary adult rat optic nerve head astrocytes Primary adult rat optic nerve head astrocytes A validated, standardized screening method for glioprotective drug candidates using primary adult rat ONHAs. Related In Vitro Glaucoma