Retina

All models

Listed alphabeticly

D

DL-AAA-induced Retinal Neovascularization and Chronic Leakage

DL-AAA-induced Retinal Neovascularization and Chronic Leakage

DL-AAA induces retinal neovascularization and chronic retinal vasculature leakage similar to patients with advanced neovascular wet AMD. 

Related In Vivo

AMD - All models

AMD - Wet AMD

Angiogenesis

Retina

L

Light Damage – Blue Light Damage

Light Damage – Blue Light Damage

The rodent blue light damage (BLD) model is a well-established model for retinal degeneration, oxidative stress and neuroinflammatory activity.

Related In Vivo

AMD - All models

AMD - Dry AMD

AMD - Geographic Atrophy

AMD - Stargardt Disease

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N

Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)

Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)

NAION-like pathology induction leads to an acute ischemia and to edema, inflammation, and acute loss of retinal ganglion cells (RGCs) and optic nerve axons.

Related In Vivo

Neuroprotection

Retina

Retinal ischemia

P

Proliferation of primary bovine retinal endothelial cells

Proliferation of primary bovine retinal endothelial cells

A physiologically relevant cellular model to assess angiogenesis.

Related In Vitro

Angiogenesis

Retina

T

Toxicity responses in human retinal pigment epithelium cells

Toxicity responses in human retinal pigment epithelium cells

An in vitro assay to help assess and predict drug-induced toxicity on the retinal pigment epithelium (RPE) cells.

Related In Vitro Tolerability and Toxicity

Retina

V

VEGF-induced Retinal Leakage

VEGF-induced Retinal Leakage

The up-regulation of VEGF leads to abnormal retinal vascular growth and leakage that causes visual impairment. Intravitreal injection of VEGF causes a transient retinal leakage mimicking the like of wet AMD and diabetic retinopathy.

Related In Vivo

AMD - All models

AMD - Wet AMD

Angiogenesis

Diabetic Retinopathy

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